R&D aimed at enhancing convenience and quality of life is a continuous journey of challenge and innovation. Recently, an increasing number of endocrinology professionals are going beyond being mere beneficiaries of R&D to actively participating in the process themselves. In this symposium, we are honored to welcome a nursing professor who has directly conducted the evaluation and selection of new medical technologies, as well as two endocrinology professors who are striving to bridge research and clinical practice through entrepreneurship and innovation. This event will provide a meaningful opportunity to share their firsthand experiences, insights, and the challenges and achievements encountered in linking research and clinical applications.

The session, titled “Senescence in Endocrine & Metabolic Disorders: Part I. Intermediary Metabolism,” aims to explore the role of cellular senescence in intermediary metabolism in depth. In particular, it will comprehensively review the latest research findings on the relationship between hepatocyte senescence and cardiovascular disease, the interplay between adipocyte inflammaging and insulin resistance, and the pathophysiological significance of pancreatic β-cell senescence, especially in type 2 diabetes mellitus. Additionally, expert insights and in-depth discussions on these topics are anticipated.

In the special interest group session of the Korean Adrenal Gland Study Group at SICEM 2025, Professor Adina Turcu from the University of Michigan will present on recent trends in the subtypes of primary aldosteronism. Professor Seunghyun Lee from Yonsei University Wonju College of Medicine will discuss systematic signatures between primary aldosteronism and primary hyperparathyroidism utilizing whole-transcriptomic datasets. Professor Seung Hun Lee from Ulsan University College of Medicine will share findings from the Korean Adrenal Disorders Study (KADS), a multicenter collaborative study on adrenal disorders in Korea.

This session will cover the latest research and clinical approaches to managing thyroid disorders, with a focus on autoimmune thyroid disease, the impact of thyroid conditions on pregnancy, and the complexities of thyroid neoplasia. Experts will share their knowledge on innovative diagnostic techniques and therapeutic strategies.